Palo Alto Investors LP

CIK 0001306923 · PALO ALTO, CA · Quarter end: 2026-06-30 · Filed on: 2026-08-19 · Open the SEC source

Palo Alto Investors LP reported 52 positions worth $723.7M as of June 30, 2026 (13F filed August 19, 2026). Largest holding: PTCT (10.4%).

Portfolio Value (AUM)Total value of the fund's US stock portfolio reported to the SEC.
$723.7M
2026 Q2
Positions
52
Top-10 ConcentrationHow much of the portfolio sits in the 10 largest holdings. High = concentrated bets.
61.3%
Est. Net Flow (Q)
2026 Q2
10 / 52 positions shown
#SymbolCompanyTypeValue% Port.Shares1YYTD
1PTCTPTC THERAPEUTICS INCSH$75.0M10.36%918,846
2ACADACADIA PHARMACEUTICALS INCSH$72.5M10.01%2,864,096
3INSMINSMED INCSH$44.1M6.10%413,980
4MIRMMIRUM PHARMACEUTICALS INCSH$40.8M5.64%348,808
5ANABANAPTYSBIO INCSH$40.7M5.63%603,489
6BMRNBIOMARIN PHARMACEUTICAL INCSH$39.1M5.40%682,777
7DYNDYNE THERAPEUTICS INCSH$36.6M5.06%1,647,521
8UTHRUNITED THERAPEUTICS CORPSH$33.9M4.69%62,587
9IRONDISC MEDICINE INCSH$30.5M4.21%416,646
10BIIBBIOGEN INCSH$30.3M4.19%140,279

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Read the 2026-Q2 quarterly report · 13F Filing Calendar

Frequently Asked Questions

What stocks does Palo Alto Investors LP hold as of Q2 2026?

Palo Alto Investors LP reported 52 positions worth $723.7M in its Q2 2026 13F filing. Largest positions: PTCT (10.4%), ACAD (10.0%), INSM (6.1%), MIRM (5.6%) and ANAB (5.6%).

What did Palo Alto Investors LP buy in Q2 2026?

No previous quarter is available yet; the comparison appears with the next filing.

What did Palo Alto Investors LP sell in Q2 2026?

No previous quarter is available yet.

13F data shows quarter-end positions, is delayed by up to 45 days and covers only long positions in US-listed securities; short positions, most derivatives and non-US assets are not reported.