EcoR1 Capital, LLC

CIK 0001587114 · SAN FRANCISCO, CA · Quarter end: 2026-06-30 · Filed on: 2026-08-14 · Open the SEC source

EcoR1 Capital, LLC reported 33 positions worth $2.06B as of June 30, 2026 (13F filed August 14, 2026). Largest holding: ZYME (29.2%).

Portfolio Value (AUM)Total value of the fund's US stock portfolio reported to the SEC.
$2.06B
2026 Q2
Positions
33
Top-10 ConcentrationHow much of the portfolio sits in the 10 largest holdings. High = concentrated bets.
86.3%
Est. Net Flow (Q)
2026 Q2
10 / 33 positions shown
#SymbolCompanyTypeValue% Port.Shares1YYTD
1ZYMEZYMEWORKS INCSH$600.4M29.19%22,970,388
2ANABANAPTYSBIO INCSH$531.9M25.86%7,880,094
3AKTSAKTIS ONCOLOGY INCSH$155.5M7.56%4,824,469
4CGONCG ONCOLOGY INCSH$106.2M5.16%1,494,300
5ETONETON PHARMACEUTICALS INCSH$78.6M3.82%2,171,938
6CRSPCRISPR THERAPEUTICS AGSH$75.8M3.68%1,389,276
7ORICORIC PHARMACEUTICALS INCSH$72.9M3.54%6,728,116
8TRAXFIRST TRACKS BIOTHERAPEUTICSSH$63.9M3.11%3,174,519
9LKFTLAKEFRONT BIOTHERAPEUTICS NVSH$50.0M2.43%1,667,119
10NGNENEUROGENE INCSH$40.0M1.94%1,271,342

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Read the 2026-Q2 quarterly report · 13F Filing Calendar

Frequently Asked Questions

What stocks does EcoR1 Capital, LLC hold as of Q2 2026?

EcoR1 Capital, LLC reported 33 positions worth $2.06B in its Q2 2026 13F filing. Largest positions: ZYME (29.2%), ANAB (25.9%), AKTS (7.6%), CGON (5.2%) and ETON (3.8%).

What did EcoR1 Capital, LLC buy in Q2 2026?

No previous quarter is available yet; the comparison appears with the next filing.

What did EcoR1 Capital, LLC sell in Q2 2026?

No previous quarter is available yet.

13F data shows quarter-end positions, is delayed by up to 45 days and covers only long positions in US-listed securities; short positions, most derivatives and non-US assets are not reported.